Co-Pis: Paul
Falkowski (IMCS,
Sang Hoon Lee (visiting microbiologist from the Polar Sciences Laboratory,
Korean Oceanographic Research and Development Institute (KORDI)
As
part of a study to decipher Antarctic climate patterns, we have been
collaborating with Dr. David Marchant (Dept. of Earth
Sciences,


The
two ices have markedly different chemistries and microbial compositions.
High-molecular weight DNA was successfully extracted
from the encased microbial communities and was detectable as a tight band, as
opposed to a broad smear, following agarose gel electrophoresis
(Figure 2A, lane 1). This hints at
remarkable DNA preservation over very long time periods
and in spite of high cosmic ray exposure; this area of
Having these ice samples in
our possession represents an unprecedented opportunity to examine ancient,
secluded and preserved microbial communities on Earth and relate their
biological, biogeochemical and genetic composition to a unique and well characterized geologic history. We hypothesize that the in situ microbial
communities have been "encased" in the ice in a senescent state over
their respective time periods, calling into question
their potential viability and genetic architecture, as well as its source and
mechanism of seeding. The overarching objectives of this study are to
characterize the metabolic state and genetic architecture of ice microbial
populations.
Our specific goals are to: (a) examine the potential recovery of viable microbes from these ice samples, and (b) to sequence the microbial residual genomes.
These analyses will allow us to
ascertain whether microorganisms remain metabolically active and perhaps
viable, over variable geologic time periods and allow, for the first time, a
comparison of functional genes in microbes that are over 7 million years old.
Viability potentially permits extrapolation of microbial communities to sustain
extended periods of dormancy (longer than a single Holocene ice age), and yet
potentially "reinfect" the environment. It further addresses the question as to
whether microbes can traverse large areas of our solar system in association
with comets. Sequencing speaks directly
to the tempo of evolution of microbes since mid-Miocene time, and to the source
of the microbes that are preserved in the ice. The funding requested here is primarily for
sequencing of the microbial DNA in collaboration with TIGR.
Dr. David R. Marchant (Dept. of Earth Sciences,
Dr. Huiming
Bao (Department of Geology & Geophysics,
Relevant publications:
MARCHANT, D.
R. and others 2002. Formation of patterned
ground and sublimation till over Miocene glacier ice
in
SUGDEN,
D. E. and others 1995. Preservation
of Miocene glacier ice in